keishi-ka-ryukotsu-borei-to

Keishi-ka-ryukotsu-borei-to is a traditional Japanese Kampo herbal medicine composed of seven crude drugs: cinnamon bark, peony root, jujube, dragon bone (fossilized bone), oyster shell, licorice root, and ginger[4]. It is primarily used in Japanese traditional medicine for treating neuropsychiatric symptoms and urogenital disorders. The formulation is believed to work through multiple mechanisms including modulation of monoamine neurotransmitters (dopamine and serotonin) in the central nervous system[6][8], regulation of the hypothalamic-pituitary-adrenal axis[5], and antioxidant effects through free radical scavenging[9]. Studies have shown it can ameliorate chronic stress-induced depressive states by preventing decreases in dopamine and serotonin in the prefrontal cortex[8]. It has also demonstrated efficacy in treating behavioral and psychological symptoms of dementia, particularly sexual delusions, potentially through effects on luteinizing hormone levels[3]. The medicine is frequently prescribed for patients with nervous constitutions who exhibit psychoneurotic symptoms, particularly those of the excessive constitution type in traditional Chinese medicine classification[6].

Brand names

TSUMURA Keishikaryukotsuboreito Extract Granules

Other names

Keishi-ka-ryukotsu-borei-toKRBTGui-Zhi-Jia-Long-Gu-Mu-Li-TangKeishikaryukotsuboreito