Drug intelligence / Profile preview

Keratosept

Development stage
Unknown
Lead developer
Visum Pharm
Modality
Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Ophthalmic
01

Overview

Keratosept is an ophthalmic solution developed by Visum Pharm, primarily indicated for the protection and repair of the corneal epithelium. The formulation is a combination of three active components: hydroxypropyl methylcellulose (HPMC), cyanocobalamin (Vitamin B12), and chlorhexidine digluconate. HPMC serves as a mucomimetic lubricant that stabilizes the tear film and increases the contact time of the solution with the ocular surface, providing relief from dryness and irritation. Cyanocobalamin supports the metabolic processes of corneal cells, facilitating re-epithelialization and tissue regeneration following injury or surgery. Chlorhexidine digluconate provides a broad-spectrum antiseptic effect, preventing secondary bacterial infections during the healing process. Keratosept is commonly used for corneal abrasions, keratitis, post-operative recovery, and conditions requiring corneal protection and hydration.

Brand names
Keratosept
Other names
Keratosept-Visum
02

Targets

MMUT (Methylmalonyl-coenzyme A mutase)1C metabolism (One-carbon metabolism)

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