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ketelin
- Development stage
- Unknown
- Lead developer
- Jiangxi Hygecon Pharmaceutical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Ketelin (咳特灵) is a traditional Chinese medicine-based combination product widely used for the relief of cough and asthma. It typically consists of an extract from *Andrographis paniculata* (containing active andrographolides) and the first-generation antihistamine chlorpheniramine maleate. The andrographis component provides anti-inflammatory, antimicrobial, and antitussive effects, while chlorpheniramine maleate acts as a histamine H1 receptor antagonist to reduce allergic symptoms and suppress the cough reflex. It is marketed as an over-the-counter (OTC) medication in China, primarily indicated for the treatment of chronic bronchitis and associated respiratory symptoms.
- Brand names
- Ketelin咳特灵
- Other names
- Ketelin Tablets咳特灵片
02
Targets
HRH1 (Histamine H1 Receptor)
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