Drug intelligence / Profile preview

Ketometa

Development stage
Unknown
Lead developer
Howards Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Ketometa is an approved fixed-dose combination drug developed by Howards Pharma, primarily used for the treatment of painful musculoskeletal conditions. It combines **ketoprofen**, a nonsteroidal anti-inflammatory drug (NSAID), with **metaxalone**, a centrally acting skeletal muscle relaxant. Ketoprofen provides analgesic and anti-inflammatory effects by inhibiting the cyclooxygenase enzymes (COX-1 and COX-2), which are responsible for the production of prostaglandins involved in pain and inflammation. Metaxalone complements this by alleviating muscle spasms, likely through general depression of the central nervous system. This dual-action approach is designed to address both the inflammatory and spasmodic components of acute musculoskeletal pain.

Brand names
Ketometa
Other names
ketoprofen + metaxalone
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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