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Ketone Rx
- Development stage
- Preclinical
- Lead developer
- Juvenescence
- Modality
- Small Molecules
- Administration
- Oral, Intracerebroventricular
01
Overview
Ketone Rx is a small molecule therapeutic candidate being developed by Juvenescence for the treatment of heart failure. The program, part of the JuvTherapeutics division, utilizes a ketone-based therapeutic approach to address metabolic dysfunction in the failing heart. In heart failure, the heart's ability to oxidize fatty acids is often impaired, leading to an energy deficit; Ketone Rx aims to provide ketone bodies as an alternative, more efficient fuel source to improve cardiac function. The development is supported by expertise from Selah Therapeutics, a joint venture between Juvenescence and the Buck Institute for Research on Aging.
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