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Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dysmenorrhea (menstrual pain), and other musculoskeletal disorders. It is also indicated for short-term relief of minor aches and pains. Ketoprofen exerts its effects primarily by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which are involved in the synthesis of prostaglandins that mediate pain, fever, and inflammation. The drug has analgesic (pain-relieving), antipyretic (fever-reducing), and anti-inflammatory properties. Additional mechanisms may include anti-bradykinin activity and lysosomal membrane stabilization[1][4][5]. Ketoprofen is available by prescription in various oral formulations.
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