Ketoprofen + cyclobenzaprine

Ketoprofen + cyclobenzaprine is a compounded pharmaceutical combination used primarily for topical pain relief. Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by inhibiting the body's production of prostaglandins, substances involved in pain, fever, and inflammation. Cyclobenzaprine is a skeletal muscle relaxant that acts centrally in the brainstem to reduce muscle spasms by inhibiting descending serotonergic pathways and decreasing activity of motor neurons. This combination is typically formulated as a topical gel or cream for localized treatment of conditions such as osteoarthritis, fibromyalgia, tendinitis, bursitis, muscle spasms, joint pain from arthritis (including rheumatoid arthritis), strains, sprains, and other musculoskeletal injuries[1][3][5][6]. The compounded formulation aims to provide both anti-inflammatory effects from ketoprofen and muscle relaxation from cyclobenzaprine.