Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
ketoprofen + omeprazole
- Development stage
- Phase 4
- Lead developer
- Viatris
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
**Ketoprofen + omeprazole** is an oral fixed-dose combination of ketoprofen, a nonselective nonsteroidal anti-inflammatory drug, and omeprazole, a proton-pump inhibitor. Ketoprofen reduces pain and inflammation by reversibly inhibiting cyclooxygenase enzymes and lowering prostaglandin synthesis, while omeprazole irreversibly inhibits the gastric proton pump to suppress acid secretion and provide gastrointestinal protection during necessary NSAID treatment. Modified-release capsule products have been marketed as Axorid and Keithon for symptomatic treatment of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis in patients with prior or elevated risk of NSAID-associated gastroduodenal ulceration or erosions. ([scottishmedicines.org.uk](https://scottishmedicines.org.uk/media/1886/606_10_ketoprofen_omeprazole_axorid_final_february_2010_for_website.pdf))
- Brand names
- AxoridKeithon
- Other names
- FDC ketoprofen + omeprazoleketoprofen/omeprazoleomeprazole + ketoprofen
02
Targets
ATP4A (Potassium–transporting ATPase alpha chain 1)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
Beyond the preview
Go deeper on ketoprofen + omeprazole.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ketoprofen + omeprazole.