Drug intelligence / Profile preview

ketorolac + loperamide + metoclopramide + nefazolin + phenazepam

Development stage
Unknown
Lead developer
Roche
Modality
Small Molecules
Administration
Oral, Intravenous, Intramuscular, Intranasal, Ophthalmic
01

Overview

This is a combination of five different medications: ketorolac (an NSAID for pain management), loperamide (an anti-diarrheal agent), metoclopramide (a prokinetic agent for gastrointestinal issues), nefazolin (listed in the query, but likely intended to be cefazolin, an antibiotic), and phenazepam (a benzodiazepine with anxiolytic and sedative properties). This specific combination is not a standard, commercially available, or approved formulation.

02

Targets

MOR (Mu opioid receptor)HTR3A (5-hydroxytryptamine receptor 3A)DRD2 (Dopamine D2 Receptor)KOR (Kappa opioid receptor)PGHS-1 (Prostaglandin G/H Synthase 1)PBP (Penicillin-binding protein family)DOR (Opioid Receptor Delta 1)

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