ketorolac + moxifloxacin + prednisolone acetate

This drug is a **fixed-dose combination** of three agents used in ophthalmology: **ketorolac** (a non-steroidal anti-inflammatory drug), **moxifloxacin** (a fourth-generation fluoroquinolone antibiotic), and **prednisolone acetate** (a synthetic corticosteroid). The combination is primarily used for the prevention and treatment of postoperative ocular inflammation and infection, especially after cataract surgery or other intraocular procedures. - **Ketorolac** inhibits prostaglandin synthesis by blocking cyclooxygenase (COX-1 and COX-2), reducing inflammation and pain[3]. - **Moxifloxacin** inhibits bacterial DNA gyrase and topoisomerase IV, preventing bacterial replication and offering broad-spectrum antibacterial activity. - **Prednisolone acetate** binds to glucocorticoid receptors to suppress inflammation by inhibiting multiple inflammatory cytokines and mediators. This combination is intended to reduce the burden of multiple separate eye drops, improve compliance, and increase patient convenience in the perioperative period[4][6][7].

Brand names

Pred-Moxi-KetorSmartDrops prednisolone acetate 1% + moxifloxacin 0.5% + ketorolac 0.4%Ixoba M

Other names

ketorolac tromethamine + moxifloxacin + prednisolone acetate