Drug intelligence / Profile preview

ketotifen + salbutamol

Development stage
Unknown
Lead developer
Zakfas Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Zakfan Plus is a fixed-dose combination medication developed by Zakfas Pharmaceutical, primarily indicated for the management of bronchial asthma and other conditions involving reversible airways obstruction. It contains two active ingredients: ketotifen and salbutamol. Ketotifen is a mast cell stabilizer and a potent H1-antihistamine that prevents the release of inflammatory mediators such as histamine and leukotrienes, thereby providing prophylactic protection against allergic triggers. Salbutamol is a short-acting beta-2 adrenergic receptor agonist that acts as a bronchodilator by relaxing the smooth muscles of the airways. Together, these components provide both preventative control and symptomatic relief of bronchospasm.

Brand names
Zakfan Plus
02

Targets

ADRB2 (β2)HRH1 (Histamine H1 Receptor)

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