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Keyanqing polysaccharide
- Development stage
- Preclinical
- Modality
- Recombinant Proteins and Enzymes, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Keyanqing polysaccharide is a protein-bound beta-glucan-rich polysaccharide extract, reportedly derived from medicinal mushrooms. While the specific mushroom source for "Keyanqing" is not directly confirmed in the available literature, similar mushroom-derived protein-bound polysaccharides—such as Polysaccharide-K (PSK) from Trametes versicolor and Ganopoly from Ganoderma lucidum—are well-studied for their immunomodulatory and antitumor properties[4][5][6]. These compounds act primarily by stimulating both innate and adaptive immune responses, enhancing cellular immunity, and promoting cytokine-mediated proliferation of immune effector cells. They are used as adjunct therapies in cancer treatment to improve survival rates when combined with chemotherapy or radiotherapy[4][5]. The mechanism involves activation of immune cells such as neutrophils and macrophages via beta-glucan receptors, leading to increased cytotoxicity against tumor cells[4].
- Brand names
- Keyanqing polysaccharide
- Other names
- Keyanqing polysaccharide
02
Targets
CLEC7A (Dectin-1)αMβ2 (Integrin αMβ2)
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