Drug intelligence / Profile preview

KHK2823

Development stage
Discontinued
Lead developer
Kyowa Kirin
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

KHK2823 is a fully human monoclonal antibody that targets CD123 (interleukin-3 receptor alpha chain), which is overexpressed on leukemic stem cells in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). By binding to and neutralizing CD123, KHK2823 aims to selectively target cancerous cells while sparing normal cells. The drug was developed for the treatment of AML and MDS but its development has been discontinued[1][2][4][5].

Other names
anti-cd123 monoclonal antibody khk2823anti-cd-123 monoclonal antibody khk2823anti-cd 123 monoclonal antibody khk2823
02

Targets

IL3RA (Interleukin 3 Receptor)

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