Drug intelligence / Profile preview

Kinezodianone R hydrochloride

Development stage
Phase 2
Lead developer
Théa Pharmaceuticals
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Kinezodianone R hydrochloride (T-4090) is a small molecule drug in development for the treatment of open-angle glaucoma and ocular hypertension. It is being developed as an ophthalmic solution and is currently in Phase 2 clinical trials. The drug acts as a Rho kinase (ROCK) inhibitor, targeting the trabecular meshwork to increase aqueous humor outflow and lower intraocular pressure—a key mechanism for managing glaucoma. The developer and sponsor of this compound is Laboratoires Théa SAS[1][2][3][7].

Brand names
T4090T-4090T 4090
Other names
kinezodianone r hclt-4090t4090t 4090
02

Targets

ROCK2 (Rho-associated coiled-coil containing protein kinase 2)ROCK1 (Rho-associated coiled-coil containing protein kinase 1)

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