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KJ-C2633
- Development stage
- Preclinical
- Lead developer
- CARsgen Therapeutics
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
- Administration
- Intravenous
01
Overview
KJ-C2633 is an innovative *in vivo* chimeric antigen receptor (CAR) T-cell therapy developed by CARsgen Therapeutics. Built on the proprietary CARvivo™ platform, KJ-C2633 is designed to target both CD19 and B-cell maturation antigen (BCMA) simultaneously. Unlike traditional *ex vivo* CAR T-cell therapies that require complex manufacturing of patient cells outside the body, this *in vivo* approach aims to generate CAR T-cells directly within the patient's body, potentially improving accessibility and reducing treatment timelines. The therapy is currently being investigated for the treatment of relapsed or refractory multiple myeloma (R/R MM) and various autoimmune diseases.
- Other names
- KJ-C2633KJ-C-2633KJ-C 2633
02
Targets
CD19 (B lymphocyte antigen CD19)BCMA (B-cell maturation antigen)
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