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klimadynon
- Development stage
- Phase 3
- Lead developer
- Bionorica
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Klimadynon is a herbal medicinal product formulated to relieve menopausal symptoms in adult women, such as hot flashes, excessive sweating, mood swings, sleep disturbances, and anxiety. Its active ingredient is a dry extract of the rhizome of black cohosh (Cimicifuga racemosa), standardized to 2.8 mg per tablet (extraction ratio typically 5-10:1 with ethanol 58% v/v as the extractant). The mechanism of action is believed to be an estrogen-like effect mediated by selective interaction with certain estrogen receptors without causing typical estrogenic changes in target tissues. Klimadynon does not contain hormones and is considered non-hormonal therapy for menopause-related complaints[1][2][3][7][8].
- Brand names
- KlimadynonKlimadynon Uno
- Other names
- black cohosh extractcimicifuga preparation BNO 1055
02
Targets
ESR1 (ERα)ESR2 (ERβ)
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