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KM-133 is an investigational small-molecule drug being developed for the treatment of psoriasis. Publicly available information from Cellceutix (now Innovation Pharmaceuticals) describes KM-133 as part of the company’s dermatology pipeline, positioned as a novel oral anti-psoriatic agent, but detailed structure, specific molecular target, and full mechanism of action have not been disclosed. It has been reported as advancing toward Phase 2 clinical trials for psoriasis, suggesting completed or ongoing early-phase evaluation of safety, tolerability, and preliminary efficacy in this chronic inflammatory skin disease characterized by keratinocyte hyperproliferation and immune dysregulation.[3][7]
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