Drug intelligence / Profile preview

KMA Bispecific

Development stage
Unknown
Lead developer
HaemaLogiX
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
01

Overview

KMA Bispecific is a bispecific monoclonal antibody developed by HaemaLogiX. It functions as an inhibitor of kappa myeloma antigen (KMA), also known as kappa myeloma antigen inhibitors. The drug is designed to target the KMA protein, which is associated with multiple myeloma and potentially other neoplasms, immune system diseases, and cardiovascular diseases. As a bispecific antibody, it can simultaneously bind two different antigens or epitopes, enhancing its therapeutic potential in cancer immunotherapy by recruiting immune cells or interfering with disease-related signaling pathways[1][7]. Its primary indication under investigation is multiple myeloma[1].

02

Targets

CD3 (T-cell surface glycoprotein CD3)Immunoglobulin light chain

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