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KN5506 is an investigational chimeric antigen receptor (CAR)-engineered natural killer (NK) cell therapy being developed by Rui Therapeutics (Shenzhen Enrui Kainuo Biotechnology Co., Ltd.). Currently in the early research and development (preclinical) stage, KN5506 is part of a pipeline of "First-in-Class" candidates derived from the company's CAR-NK technology platform. The therapy is designed to harness the innate cytotoxic potential of NK cells, which are modified to express a CAR that directs them to recognize and eliminate cells expressing a specific, though currently undisclosed, target antigen. While the primary therapeutic indication has not been revealed, the platform generally targets oncology or autoimmune conditions.
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