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KNA-145 is a gene therapy drug candidate developed by Kinea Bio. It is in preclinical development for the treatment of congenital muscular dystrophy, a group of inherited muscle disorders characterized by muscle weakness and degeneration present at birth. The specific mechanism of action, molecular target, and delivery vector for KNA-145 have not been publicly disclosed as of June 2025. The therapy represents an investigational approach aimed at addressing the underlying genetic causes of congenital muscular dystrophy[1][2][5].
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