Drug intelligence / Profile preview

KOfactor

Development stage
Preclinical
Lead developer
KoDiscovery
Modality
Small Molecules
Administration
Oral
01

Overview

KOfactor is a dietary supplement developed by KoDiscovery, formulated as a proprietary synergistic blend of three natural phytochemicals: luteolin, rutin, and epigallocatechin gallate (EGCG). The product is designed based on research suggesting that these specific polyphenols, when combined in a precise ratio, exhibit enhanced anti-proliferative and pro-apoptotic activity against cancer cells compared to the individual components. In vitro studies have demonstrated the combination's ability to induce apoptosis and inhibit the growth of various cancer cell lines. While marketed as a nutraceutical rather than a pharmaceutical drug, KoDiscovery includes KOfactor in its development pipeline for potential applications in oncological support and cancer cell killing.

Brand names
KOfactor
Other names
KoDiscovery KOfactor
02

Targets

NF-κBDNMT (DNA methyltransferase)CASP (Caspase family)PI3K (Phosphoinositide-3-kinase regulatory subunit 6)

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