konjac glucomannan + inulin

Konjac glucomannan + inulin is a combination of two plant-based polysaccharides with prebiotic properties, commonly used as a dietary supplement to promote gut health and metabolic balance. Konjac glucomannan (KGM), derived from the tuber of Amorphophallus konjac, is a water-soluble polysaccharide primarily composed of β-1,4-linked D-glucose and D-mannose units, and is known for its high viscosity and ability to form gels. Inulin, typically extracted from chicory root (Cichorium intybus), is a fructan composed mainly of β-2,1-linked fructose units with a terminal glucose moiety. When consumed together, these fibers exhibit synergistic effects on gut microbiota, mucosal barrier function, and immune modulation via enhancement of short-chain fatty acid production and normalization of tight junction protein expression. Animal studies and limited clinical observations indicate that the combination reduces blood glucose more effectively than either component alone and mitigates colitis and mucosal barrier dysfunction, likely by prebiotic effects that positively modulate the intestinal microbiota, improve tight junction integrity, and exert anti-inflammatory actions. This combination is investigated primarily for its effects on metabolic diseases (notably diabetes and hyperlipidemia), obesity, and inflammatory bowel diseases, but is not classified or regulated as a pharmaceutical drug.

Other names

konjac and inulinKGM + inulinKI compositionkonjac glucomannan and inulinKGM + I