Drug intelligence / Profile preview

Korea Univ. College of Medicine MSTN compound 1

Development stage
Preclinical
Lead developer
Korea University College of Medicine
Modality
Peptides
01

Overview

Korea Univ. College of Medicine MSTN compound 1: sourced facts only. name: "This work establishes compound 1 as a lead prodrug for MSTN antagonism in muscle atrophy." [PMID:42865977]; target: "This work establishes compound 1 as a lead prodrug for MSTN antagonism in muscle atrophy." [PMID:42865977]; developer: "Department of Anatomy, Korea University College of Medicine, 73 Inchon-ro, Seongbuk-gu, Seoul 02841, Republic of Korea." [PMID:42865977]; modality: "We designed all-d tripeptide prodrug mimetics of the MSTN prodomain minimum active 23-mer fragment." [PMID:42865977]; stage: "In vivo, compound 1 increased soleus mass and grip strength in mice." [PMID:42865977]

02

Targets

GDF8 (Myostatin)

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