Drug intelligence / Profile preview

korean red ginseng extract

Development stage
Phase 4
Lead developer
Korea Ginseng Corporation
Modality
Small Molecules
Administration
Oral
01

Overview

Korean red ginseng extract is a concentrated preparation derived from the root of Panax ginseng C.A. Meyer that has been steamed and dried to produce "red" ginseng. It is widely used as a dietary supplement for its adaptogenic properties—purportedly helping the body resist stress—and for immunomodulatory effects. The main active constituents are a group of saponins called ginsenosides. Mechanistically, Korean red ginseng appears to modulate immune function by increasing T cells (CD3+, CD4+, CD8+), B cells, and white blood cell counts[6]. It also exhibits antioxidant activity and may influence drug metabolism by affecting cytochrome P450 enzymes and drug transporters such as P-glycoprotein[5]. Clinical studies suggest possible benefits in improving cognitive function, supporting immune health, reducing fatigue/stress responses, modestly lowering blood glucose levels in diabetes[2][9], and potentially augmenting treatment in depression[10]. However, most uses are not confirmed by large-scale clinical trials or regulatory approval.

Brand names
CheongKwanJangKorea Ginseng Corp Red Ginsengother regional and company-specific brands
Other names
Panax ginseng extractAsian ginseng extractKorean ginseng extractRed ginseng extract
02

Targets

OAT1 (Organic anion transporter 1)IL-2 (Interleukin 2)NFAT (NFAT family)SLC22A8 (Organic anion transporter 3)CYP3A (CYP3A family)

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