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Kosnate-D Plus
- Development stage
- Unknown
- Lead developer
- AGP
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Kosnate-D Plus (referred to in some sources as Koselugo-D Plus) is a multi-ingredient nutritional supplement developed and marketed by AGP in Pakistan for the maintenance of bone health and the treatment or prevention of bone disorders such as osteoporosis, osteomalacia, and hypoparathyroidism. It is formulated as an oral powder sachet containing a combination of Ossein Mineral Complex (providing organic bone matrix and calcium), Vitamin D3 (cholecalciferol), Vitamin K2 (menaquinone-7), Vitamin C, Magnesium, and Zinc. This combination works synergistically to promote bone mineralization, enhance calcium absorption via the Vitamin D receptor (VDR), and support the carboxylation of bone proteins like osteocalcin through Vitamin K-dependent gamma-carboxylase (GGCX).
- Brand names
- Kosnate-D Plus
- Other names
- Koselugo-D Plus
02
Targets
CaSR (Extracellular calcium-sensing receptor)VDR (Vitamin D receptor)GGCX (Vitamin K-dependent gamma-glutamyl carboxylase)
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