Drug intelligence / Profile preview

KRK-TTA

Development stage
Unknown
Lead developer
Lamark
Modality
RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

**KRK-TTA** is an investigational therapeutic candidate being developed by **Lamark** (Lamark Biotech) for the treatment of **lung cancer**. According to company pipeline documentation, the asset is currently in **Phase 1/2** clinical development. Lamark Biotech specializes in the development of **tRNA-based medicines** designed to address diseases caused by nonsense mutations. Their platform utilizes engineered tRNAs to suppress premature stop codons, which allows the cellular machinery to read through the mutation and produce a full-length, functional protein. While the specific molecular target for KRK-TTA has not been publicly disclosed, the program represents an application of tRNA technology to oncology.

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