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KSP-910638G
- Development stage
- Phase 1
- Lead developer
- University of Michigan
- Modality
- Peptides, Small Molecules
- Administration
- Oral, Topical (for Endoscopic Or Surgical Application)
01
Overview
KSP-910638G is a synthetic heptapeptide imaging agent labeled with the near-infrared dye IRDye800CW. It specifically targets human epithelial growth factor receptor type 2 (HER2; also known as ErbB2), a receptor overexpressed in certain cancers. The compound is designed for molecular imaging applications, particularly for the early detection of gastrointestinal malignancies and potentially other HER2-positive tumors. Developed by the University of Michigan College of Engineering, it has been evaluated in Phase 1 clinical trials to assess its safety when administered orally or topically for fluorescence-guided surgery and diagnostic purposes[1][2][3][6].
- Other names
- IRDye800CW-labeled heptapeptide KSP-910638GIRDye-800CW-labeled heptapeptide KSP-910638GIRDye 800CW-labeled heptapeptide KSP-910638G
02
Targets
ERBB2 (Erb-b2 receptor tyrosine kinase 2)
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