Drug intelligence / Profile preview

KT032

Development stage
Phase 1
Lead developer
Nanjing Kati Medical Technology
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

KT032 is an **autologous CAR-T cell therapy** targeting **mesothelin (MSLN)**, developed for the treatment of mesothelin-expressing advanced solid tumors. KT032 utilizes genetically engineered autologous T cells designed to recognize and kill cells expressing mesothelin, a protein overexpressed in certain cancers such as ovarian cancer, mesothelioma, and pancreatic cancer. The drug is in early clinical development and is being investigated for safety and anti-tumor efficacy. The therapy is developed by Nanjing Kati Medical Technology and represents an immunotherapy approach, harnessing the cytotoxic potential of T cells redirected against tumor antigens via a chimeric antigen receptor targeting mesothelin.

02

Targets

Mesothelin

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