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Ku Qin Formula

Development stage: Unknown
Lead developer: Yueyang Hospital of Integrated Traditional Chinese and Western Medicine
Administration: Oral

Overview

Ku Qin Formula is a Traditional Chinese Medicine (TCM) herbal preparation developed by the Yueyang Hospital of Integrative Medicine at the Shanghai University of Traditional Chinese Medicine. It is primarily investigated for the treatment of prurigo nodularis, a chronic inflammatory skin condition characterized by symmetric, intensely pruritic nodules. The formula's name is derived from its two primary constituent herbs: Ku Shen (Sophora flavescens) and Huang Qin (Scutellaria baicalensis), which are traditionally used in TCM to clear heat and dry dampness. In clinical research, the formula is being evaluated as a sequential or adjunctive therapy alongside the IL-4/IL-13 inhibitor dupilumab. The study aims to determine if the addition of Ku Qin Formula can accelerate itch relief, improve skin lesion clearance, and potentially allow for a shorter duration of dupilumab treatment while maintaining long-term disease control and safety.

Other names: Ku Qin FormulaKuqin Formula

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