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kuhuang
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Oral, Intravenous (injection)
01
Overview
Kuhuang (苦黄) is a traditional Chinese medicine formulation used primarily for the treatment of liver-related conditions such as cholestatic jaundice and viral hepatitis. It is available in both granule and injectable forms. Clinical studies have explored its efficacy in improving symptoms of cholestatic jaundice and viral hepatitis by supporting liver function and reducing bilirubin levels[1][2]. The mechanism of action is not fully elucidated but is believed to involve hepatoprotective effects through anti-inflammatory and antioxidative pathways typical of many TCM herbal formulations. Kuhuang is developed within the framework of traditional Chinese medicine rather than by a single pharmaceutical company.
- Brand names
- 苦黄颗粒苦黄注射液
- Other names
- 苦黄Ku HuangKu Huang granuleKu Huang injection
02
Targets
PPARG (Peroxisome proliferator-activated receptor gamma)CYP7A1 (Cholesterol 7alpha-hydroxylase)CYP8B1 (Sterol 12α-hydroxylase)
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