Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
KuiAnNingFang
- Development stage
- Preclinical
- Lead developer
- Anhui University of Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
KuiAnNingFang (KANF) is a Traditional Chinese Medicine (TCM) formula developed for the treatment of ulcerative colitis (UC), a chronic and relapsing inflammatory bowel disease. The formula exerts its therapeutic effects by modulating the gut microbiota and suppressing key inflammatory signaling pathways, specifically the NF-κB and NLRP3 inflammasome pathways. By inhibiting these pathways, KANF reduces the production of pro-inflammatory cytokines, helps restore the intestinal mucosal barrier, and corrects microbial dysbiosis. It is primarily studied in preclinical and clinical settings in China as an alternative or complementary therapy for inflammatory conditions of the colonic mucosa.
- Other names
- Kui An Ning FangKuiAnNing formula
02
Targets
NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)NF-κB
Beyond the preview
Go deeper on KuiAnNingFang.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on KuiAnNingFang.