Drug intelligence / Profile preview

kushen pian

Development stage
Unknown
Lead developer
Liaoning Jindan Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Kushen Pian is a traditional Chinese medicine (TCM) tablet manufactured by Liaoning Jindan Pharmaceutical, derived from the root of *Sophora flavescens*. It is an approved pharmaceutical product in China, primarily used for its heat-clearing, dampness-drying, and insecticidal properties. The active components are quinolizidine alkaloids, specifically matrine and oxymatrine, which provide anti-inflammatory, antibacterial, and anti-itch effects. Clinical indications typically include damp-heat induced diarrhea, jaundice, leukorrhea with reddish discharge, and skin ailments such as eczema and pruritus.

Brand names
Kushen Pian
Other names
Sophora flavescens tabletsKu Shen Pian
02

Targets

SCN9A (Sodium channel protein type 9 subunit alpha)IL-6 (Interleukin 6)PIEZO1 (Piezo-type mechanosensitive ion channel component 1)PTAFR (Platelet-activating factor receptor)TNFA (Tumor necrosis factor alpha (soluble))KOR (Kappa opioid receptor)

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