kushenol a

Kushenol A is a flavonoid compound isolated from the root of Sophora flavescens. It acts as a **non-competitive tyrosinase inhibitor**, blocking the conversion of L-tyrosine to L-DOPA, and inhibits **alpha-glucosidase** and **beta-amylase** enzymes. Kushenol A demonstrates **antioxidant**, **enzyme inhibitory**, and **anti-proliferative** activities, including reported suppression of cancer cell growth through inhibition of the **PI3K/AKT/mTOR signaling pathway**. Its primary research indications are in dermatology (skin whitening, anti-aging cosmetics), metabolic disorders (enzyme inhibition), and oncology research[1][3][5][9][10]. It is not approved for pharmaceutical use; current availability is for research purposes only.

Other names

kushenol a(-)-kushenol a(2S)-5,7-dihydroxy-2-(2-hydroxyphenyl)-8-[(2R)-5-methyl-2-prop-1-en-2-ylhex-4-enyl]-2,3-dihydrochromen-4-oneLeachianone E