Drug intelligence / Profile preview

Kwai

Development stage
Unknown
Lead developer
Advance Pharma
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Kwai is a standardized dehydrated garlic powder supplement derived from *Allium sativum*, manufactured by Lichtwer Pharma. It is formulated as a non-enteric-coated tablet standardized to contain 1.3% allicin, the primary bioactive component. Kwai exerts its therapeutic effects by inhibiting the cyclooxygenase-mediated thromboxane-synthesis pathway, thereby reducing platelet aggregation. It also inhibits cholesterol biosynthesis and enhances fibrinolysis. The supplement has been investigated for the treatment and prevention of cardiovascular conditions, including hypertension, atherosclerosis, and hypercholesterolemia. Clinical research, including studies at the Medizinische Universität Wien, has evaluated its impact on platelet function and potential interactions with nonsteroidal anti-inflammatory drugs (NSAIDs) like diclofenac.

Brand names
Kwai
Other names
garlic powderAllium sativum
02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)TBXAS1 (Thromboxane A2 synthase)

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