Drug intelligence / Profile preview

KWZY-9a

Development stage
Unknown
Lead developer
China Pharmaceutical University
01

Overview

KWZY-9a: sourced facts only. name: "SAR analysis revealed that compound 9a exhibited promising PARP1 inhibitory activity and demonstrated significant anti-proliferative effects in both breast cancer MDA-MB-231 and ovarian cancer A2780 cells." [PMID:41192280]; target: "SAR analysis revealed that compound 9a exhibited promising PARP1 inhibitory activity and demonstrated significant anti-proliferative effects in both breast cancer MDA-MB-231 and ovarian cancer A2780 cells." [PMID:41192280]; developer: "Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, People's Republic of China." [PMID:41192280]; stage: "SAR analysis revealed that compound 9a exhibited promising PARP1 inhibitory activity and demonstrated significant anti-proliferative effects in both breast cancer MDA-MB-231 and ovarian cancer A2780 cells." [PMID:41192280]

02

Targets

PARP1 (Poly (adp-ribose) polymerase 1)

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