Drug intelligence / Profile preview

KY1104

Development stage
Preclinical
Lead developer
KYDES Pharmaceuticals
Modality
Hydrogel Systems → Drug Delivery Systems, Implantable Devices → Device-based Delivery → Drug Delivery Systems
Administration
Topical
01

Overview

KY1104 is a topical microbicide being developed by KYDES Pharmaceuticals for the prevention of HIV infection. Currently in the preclinical stage, the drug is designed for topical application to provide a protective barrier against viral transmission. Its mechanism of action involves the inhibition of viral replication and the reduction of viral integration into the host cell's genome, thereby preventing the establishment of a permanent infection.

02

Targets

Integrase allosteric pocket (HIV)

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