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Kyowa Kirin ChemR23 compound 14f
- Development stage
- Unknown
- Lead developer
- Kyowa Kirin
01
Overview
Kyowa Kirin ChemR23 compound 14f: sourced facts only. name: "Through sequential structure-activity relationship studies regarding (i) the side chain of the N-acylsulfonamide moiety, (ii) the 5-position of the thiazole ring, and (iii) the 1,2,4-oxadiazol-5-one moiety, we have succeeded in finding a potent thiazole-based ChemR23 inhibitor, 14f (IC80 = 12 nM)." [PMID:35063894]; target: "Through sequential structure-activity relationship studies regarding (i) the side chain of the N-acylsulfonamide moiety, (ii) the 5-position of the thiazole ring, and (iii) the 1,2,4-oxadiazol-5-one moiety, we have succeeded in finding a potent thiazole-based ChemR23 inhibitor, 14f (IC80 = 12 nM)." [PMID:35063894]; developer: "Modality Research Laboratories 2, R&D Division, Kyowa Kirin Co., Ltd., 1188 Shimotogari, Nagaizumi-cho, Sunto-gun, Shizuoka 411-8731, Japan. Electronic address: [email protected]." [PMID:35063894]
02
Targets
CMKLR1 (Chemokine-like receptor 1)
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