Drug intelligence / Profile preview

l-165041

Development stage
Preclinical
Modality
Small Molecules
01

Overview

L‑165041 is a synthetic small molecule belonging to the class of alkyl‑phenylketones. It is primarily used as an experimental compound in research settings and is not approved for clinical use. The compound has been studied as a selective agonist of peroxisome proliferator‑activated receptor beta/delta (PPARβ/δ), a nuclear hormone receptor involved in lipid metabolism, glucose homeostasis, and energy balance. By activating PPARβ/δ, L‑165041 can modulate gene expression related to fatty acid oxidation and energy expenditure. Its main applications are in preclinical studies investigating metabolic diseases such as obesity, diabetes, dyslipidemia, and cardiovascular disorders[1][6][9].

Other names
{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid79558-09-12-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acidAceticacid, 2-[4-[3-(4-acetyl–3-hydroxy–2-propylphenoxy)propoxy]phenoxy]-
02

Targets

PPARD (Peroxisome proliferator–activated receptor delta)

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