Drug intelligence / Profile preview

L-741626

Development stage
Preclinical
Modality
Small Molecules
Administration
Intraperitoneal, Subcutaneous
01

Overview

L-741626 is a potent and selective antagonist for the dopamine receptor D₂. It has good selectivity over the related D₃ and D₄ subtypes. It is used primarily in laboratory research to study the roles of D₂ receptors in the brain and has been explored for its effects on various diseases, including cancer (hepatocellular carcinoma) by acting on pathways like the MAPK/ERK signaling pathway via non-dopamine receptor targets.

Other names
L741626L-741626L 741626
02

Targets

DRD3 (Dopamine receptor D3)DRD4 (Dopamine D4 Receptor)DRD2 (Dopamine D2 Receptor)

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