L-ICG

**L-ICG** is an investigational locally injected fluorescent imaging formulation composed of indocyanine green and lidocaine mucilage. It was developed for near-infrared fluorescence image-guided breast-conserving surgery, where peritumoral administration enables real-time visualization of the tumor boundary and supports intraoperative margin assessment. In a prospective study in patients with breast cancer, L-ICG-guided surgery was associated with a final positive-margin rate of 1.9% after intraoperative management; no serious adverse events were reported. ([link.springer.com](https://link.springer.com/article/10.1007/s10549-025-07609-6))

Other names

lidocaine mucilage-ICGlidocaine mucilage-indocyanine green