l-malic acid

L-malic acid is a naturally occurring dicarboxylic acid that serves as a critical intermediate in the citric acid cycle (Krebs cycle), playing a vital role in cellular energy production by facilitating the transport of NADH from the cytosol to the mitochondria. Pharmaceutically, it is utilized in various capacities: as a sialagogue in topical formulations (such as sprays or lozenges) to treat xerostomia (dry mouth) by stimulating saliva production through its acidic profile; as an electrolyte replenisher in parenteral nutrition; and in combination therapies for liver protection and recovery. Beijing Minkan Baicao Pharmaceutical Technology includes L-malic acid in its development pipeline, likely focusing on standardized formulations or generic versions for the Chinese market.

Other names

(S)-hydroxybutanedioic acidL-苹果酸malic acid