Drug intelligence / Profile preview

L-menthol preparation NPO-11

Development stage
Phase 3
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Administration
Topical (spray Onto Gastric Mucosa)
01

Overview

L-menthol preparation NPO-11 is a pharmaceutical formulation containing L-menthol, developed for its potential anti-peristaltic activity. When sprayed directly onto the gastric mucosa, it relaxes gastrointestinal smooth muscle, leading to suppression of gastric peristalsis. This effect is particularly beneficial during upper gastrointestinal (GI) endoscopic procedures by improving visualization and access through reduced movement of the stomach lining[1][2].

Other names
L-menthol preparation NPO-11
02

Targets

LTCC (Voltage-gated calcium channel (L-type))

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