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l-methionine + hibiscus sabdariffa + boswellia leaf extract
- Development stage
- Unknown
- Lead developer
- Biohealth Italia
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
ACIDIF PLUS® is a phytotherapeutic combination product consisting of the amino acid L-methionine, Hibiscus sabdariffa extract, and Boswellia serrata leaf extract. It is primarily indicated for the treatment and prevention of recurrent uncomplicated urinary tract infections (UTIs) in women. L-methionine acts as a urinary acidifier, creating an environment less favorable for bacterial growth. Hibiscus sabdariffa provides antimicrobial and anti-inflammatory properties, while Boswellia serrata contributes additional anti-inflammatory activity, specifically through the inhibition of 5-lipoxygenase. The product has been evaluated in clinical trials as a non-antibiotic alternative for UTI symptom relief and for the prevention of postoperative UTIs following pelvic reconstructive surgery.
- Brand names
- ACIDIF PLUS
- Other names
- L-methionine + Hibiscus sabdariffa + Boswellia serrata
02
Targets
ALOX5 (Arachidonate 5-lipoxygenase)
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