l-ornithine l-aspartate

**L-ornithine l-aspartate** is an ammonia-lowering amino-acid salt composed of L-ornithine and L-aspartate, marketed in certain countries as **Hepa-Merz**. It supports ammonia detoxification through two endogenous pathways: hepatic urea synthesis and glutamine synthesis in liver and peripheral tissues, thereby reducing hyperammonemia that contributes to hepatic encephalopathy. It is supplied as oral granules and as an intravenous infusion concentrate, and is principally used for latent or manifest hepatic encephalopathy associated with impaired liver detoxification, including cirrhosis. ([merztherapeutics.com](https://merztherapeutics.com/science/hepatology/))

Brand names

Hepa-Merz

Other names

LOLAL-ornithine-L-aspartate门冬氨酸鸟氨酸