l-ornithine l-aspartate + silymarin (Bennet Pharmaceuticals Ltd.)

Benoliv LS is a combination hepatoprotective medication developed and marketed by Bennet Pharmaceuticals. It is composed of **L-ornithine L-aspartate (LOLA)** and **silymarin**. L-ornithine L-aspartate is a stable salt of two natural amino acids that facilitates the detoxification of ammonia by stimulating the urea cycle and glutamine synthesis, which is critical in managing hepatic encephalopathy and chronic liver diseases. Silymarin, a standardized extract from the seeds of the milk thistle (*Silybum marianum*), contains a mixture of flavonolignans (primarily silybin) that exert antioxidant, anti-inflammatory, and membrane-stabilizing effects. Together, these components work to reduce toxic ammonia levels, protect hepatocytes from oxidative stress, and promote the regeneration of liver tissue. Benoliv LS is typically indicated for chronic inflammatory liver conditions, fatty liver, and cirrhosis.

Brand names

Benoliv LS

Other names

L-Ornithine L-Aspartate and Silymarin Combination