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L-Vincristine
- Development stage
- Preclinical
- Lead developer
- InnoMedica
- Modality
- Small Molecules, Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Intravenous
01
Overview
L-Vincristine is a preclinical-stage liposomal nanocarrier formulation of vincristine being developed by InnoMedica Holding AG for the treatment of leukemia. The drug utilizes InnoMedica's proprietary liposomal nanocarrier technology platform to deliver the active ingredient vincristine, a vinca alkaloid chemotherapy agent. Vincristine works by disrupting microtubule formation during cell division, specifically by binding to tubulin and inhibiting its polymerization, making it effective against rapidly dividing cancer cells. The liposomal formulation is designed to improve drug delivery and potentially reduce the dose-limiting neurotoxicity associated with conventional vincristine while maintaining or enhancing therapeutic efficacy.
- Other names
- vincristine liposomal nanocarrierliposomal vincristine
02
Targets
TUBB (Tubulin (alpha and beta subunits))
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