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L14

Development stage: Preclinical
Lead developer: BIFIDO
Modality: Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration: Oral

Overview

L14 is a probiotic live biotherapeutic product (LBP) consisting of a specific *Bifidobacterium* strain, currently under development by BIFIDO for the treatment of obesity and the reduction of body fat. As a microbial therapy, it aims to modulate the gut microbiota to influence metabolic processes associated with weight management and adiposity. The program is currently in the preclinical or early clinical stages, with development milestones and timeline bars projected for the 2026-2027 period according to the sponsor's pipeline roadmap.

Other names: Bifidobacterium L14

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