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**LA-858** is an Allero Therapeutics preclinical allergen immunotherapy candidate for food allergy and pollen allergy. It uses Allero's SOMIT specific oromucosal immunotherapy platform: a mouth patch designed to retain allergen antigen at the oral mucosa and promote antigen-specific immune tolerance with tolerogenic bacterial-particle and TLR-binding components. Allero describes SOMIT as a non-invasive platform intended to induce durable antigen-specific tolerance without global immunosuppression. ([allerotherapeutics.com](https://www.allerotherapeutics.com/technology-1))
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