Drug intelligence / Profile preview

LAC-Shield

Development stage
Unknown
Lead developer
Morinaga Milk Industry
Modality
Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration
Oral
01

Overview

LAC-Shield is a postbiotic functional ingredient consisting of the heat-killed bacterial strain *Lactobacillus paracasei* MCC1849. Developed by Morinaga Milk Industry, it is designed to support immune function by interacting with immunocytes in the small intestine's Peyer's patches. This interaction stimulates the production of key cytokines, including interleukin-12 (IL-12) and type I interferons, which play critical roles in antiviral and overall immune responses. Clinical research indicates that LAC-Shield may help reduce the risk and severity of common cold symptoms, improve mood states under stress, and enhance the efficacy of influenza vaccinations, particularly in elderly populations. As a heat-killed (non-viable) ingredient, it is highly stable and suitable for use in a wide range of food, beverage, and dietary supplement applications where traditional live probiotics might not survive processing or storage.

Brand names
LAC-Shield
Other names
Lactobacillus paracasei MCC1849heat-killed Lactobacillus paracasei MCC1849inactivated Lactobacillus paracasei MCC1849
02

Targets

IL12 (Interleukin-12)IFNE (Interferon epsilon)

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