Drug intelligence / Profile preview

Lacrisol

Development stage
Phase 4
Lead developer
Bruschettini
Modality
Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems
Administration
Ophthalmic
01

Overview

Lacrisol is an approved ophthalmic solution developed and manufactured by Bruschettini for the treatment of alterations of the ocular surface, including dry eye syndrome (lacrimal insufficiency) and for the disinfection of the ocular mucosa. It is a fixed-dose combination of hypromellose (hydroxypropyl methylcellulose) and benzalkonium chloride. Hypromellose acts as a lubricant and humectant that mimics natural tears, increasing viscosity and moisture retention on the corneal surface. Benzalkonium chloride serves as an antiseptic agent to disinfect the ocular surface. Lacrisol is administered topically as eye drops.

Brand names
Lacrisol
Other names
benzalkonium chloride + hydroxypropyl methylcellulosebenzalkonium chloride + hypromellosehypromellose + benzalkonium chloride

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